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Monitoring Replication Protein A (RPA) dynamics in homologous recombination through site-specific incorporation of non-canonical amino acids

An essential coordinator of all DNA metabolic processes is Replication Protein A (RPA). RPA orchestrates these processes by binding to single-stranded DNA (ssDNA) and interacting with several other DNA binding proteins. Determining the real-time kinetics of single players such as RPA in the presence...

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Detalles Bibliográficos
Autores principales: Pokhrel, Nilisha, Origanti, Sofia, Davenport, Eric Parker, Gandhi, Disha, Kaniecki, Kyle, Mehl, Ryan A., Greene, Eric C., Dockendorff, Chris, Antony, Edwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766198/
https://www.ncbi.nlm.nih.gov/pubmed/28934470
http://dx.doi.org/10.1093/nar/gkx598