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CLIP-seq analysis of multi-mapped reads discovers novel functional RNA regulatory sites in the human transcriptome
Crosslinking or RNA immunoprecipitation followed by sequencing (CLIP-seq or RIP-seq) allows transcriptome-wide discovery of RNA regulatory sites. As CLIP-seq/RIP-seq reads are short, existing computational tools focus on uniquely mapped reads, while reads mapped to multiple loci are discarded. We pr...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766199/ https://www.ncbi.nlm.nih.gov/pubmed/28934506 http://dx.doi.org/10.1093/nar/gkx646 |