hnRNP L controls HPV16 RNA polyadenylation and splicing in an Akt kinase-dependent manner

Inhibition of the Akt kinase activates HPV16 late gene expression by reducing HPV16 early polyadenylation and by activating HPV16 late L1 mRNA splicing. We identified ‘hot spots’ for RNA binding proteins at the early polyA signal and at splice sites on HPV16 late mRNAs. We observed that hnRNP L was...

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Detalles Bibliográficos
Autores principales: Kajitani, Naoko, Glahder, Jacob, Wu, Chengjun, Yu, Haoran, Nilsson, Kersti, Schwartz, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766200/
https://www.ncbi.nlm.nih.gov/pubmed/28934469
http://dx.doi.org/10.1093/nar/gkx606

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766200/
https://www.ncbi.nlm.nih.gov/pubmed/28934469
http://dx.doi.org/10.1093/nar/gkx606

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