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Regulation of chromatin folding by conformational variations of nucleosome linker DNA

Linker DNA conformational variability has been proposed to direct nucleosome array folding into more or less compact chromatin fibers but direct experimental evidence for such models are lacking. Here, we tested this hypothesis by designing nucleosome arrays with A-tracts at specific locations in th...

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Detalles Bibliográficos
Autores principales: Buckwalter, Jenna M., Norouzi, Davood, Harutyunyan, Anna, Zhurkin, Victor B., Grigoryev, Sergei A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766201/
https://www.ncbi.nlm.nih.gov/pubmed/28934465
http://dx.doi.org/10.1093/nar/gkx562