Tuning RNA folding and function through rational design of junction topology

Structured RNAs such as ribozymes must fold into specific 3D structures to carry out their biological functions. While it is well-known that architectural features such as flexible junctions between helices help guide RNA tertiary folding, the mechanisms through which junctions influence folding rem...

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Detalles Bibliográficos
Autores principales: Daher, May, Mustoe, Anthony M., Morriss-Andrews, Alex, Brooks III, Charles L., Walter, Nils G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766210/
https://www.ncbi.nlm.nih.gov/pubmed/28934478
http://dx.doi.org/10.1093/nar/gkx614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766210/
https://www.ncbi.nlm.nih.gov/pubmed/28934478
http://dx.doi.org/10.1093/nar/gkx614

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