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Improving pairwise comparison of protein sequences with domain co-occurrence
Comparing and aligning protein sequences is an essential task in bioinformatics. More specifically, local alignment tools like BLAST are widely used for identifying conserved protein sub-sequences, which likely correspond to protein domains or functional motifs. However, to limit the number of false...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766236/ https://www.ncbi.nlm.nih.gov/pubmed/29293498 http://dx.doi.org/10.1371/journal.pcbi.1005889 |