Palmitate-induced ER stress and inhibition of protein synthesis in cultured myotubes does not require Toll-like receptor 4

Saturated fatty acids, such as palmitate, are elevated in metabolically dysfunctional conditions like type 2 diabetes mellitus. Palmitate has been shown to impair insulin sensitivity and suppress protein synthesis while upregulating proteolytic systems in skeletal muscle. Increased sarco/endoplasmic...

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Detalles Bibliográficos
Autores principales: Perry, Ben D., Rahnert, Jill A., Xie, Yang, Zheng, Bin, Woodworth-Hobbs, Myra E., Price, S. Russ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766250/
https://www.ncbi.nlm.nih.gov/pubmed/29329354
http://dx.doi.org/10.1371/journal.pone.0191313

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766250/
https://www.ncbi.nlm.nih.gov/pubmed/29329354
http://dx.doi.org/10.1371/journal.pone.0191313

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