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Palmitate-induced ER stress and inhibition of protein synthesis in cultured myotubes does not require Toll-like receptor 4

Saturated fatty acids, such as palmitate, are elevated in metabolically dysfunctional conditions like type 2 diabetes mellitus. Palmitate has been shown to impair insulin sensitivity and suppress protein synthesis while upregulating proteolytic systems in skeletal muscle. Increased sarco/endoplasmic...

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Detalles Bibliográficos
Autores principales:	Perry, Ben D., Rahnert, Jill A., Xie, Yang, Zheng, Bin, Woodworth-Hobbs, Myra E., Price, S. Russ
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766250/ https://www.ncbi.nlm.nih.gov/pubmed/29329354 http://dx.doi.org/10.1371/journal.pone.0191313

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