Integration of pan-cancer transcriptomics with RPPA proteomics reveals mechanisms of epithelial-mesenchymal transition

Integrating data from multiple regulatory layers across cancer types could elucidate additional mechanisms of oncogenesis. Using antibody-based protein profiling of 736 cancer cell lines, along with matching transcriptomic data, we show that pan-cancer bimodality in the amounts of mRNA, protein, and...

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Detalles Bibliográficos
Autores principales: Koplev, Simon, Lin, Katie, Dohlman, Anders B., Ma’ayan, Avi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766255/
https://www.ncbi.nlm.nih.gov/pubmed/29293502
http://dx.doi.org/10.1371/journal.pcbi.1005911

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766255/
https://www.ncbi.nlm.nih.gov/pubmed/29293502
http://dx.doi.org/10.1371/journal.pcbi.1005911

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