Transcriptional inaccuracy threshold attenuates differences in RNA-dependent DNA synthesis fidelity between retroviral reverse transcriptases

In M13mp2 lacZα forward mutation assays measuring intrinsic fidelity of DNA-dependent DNA synthesis, wild-type human immunodeficiency virus type 1 (HIV-1) RTs of group M/subtype B previously showed >10-fold higher error rates than murine leukaemia virus (MLV) and avian myeloblastosis virus (AMV)...

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Detalles Bibliográficos
Autores principales: Sebastián-Martín, Alba, Barrioluengo, Verónica, Menéndez-Arias, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766491/
https://www.ncbi.nlm.nih.gov/pubmed/29330371
http://dx.doi.org/10.1038/s41598-017-18974-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766491/
https://www.ncbi.nlm.nih.gov/pubmed/29330371
http://dx.doi.org/10.1038/s41598-017-18974-8

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