Large-scale aggregation analysis of eukaryotic proteins reveals an involvement of intrinsically disordered regions in protein folding

A subset of the proteome is prone to aggregate formation, which is prevented by chaperones in the cell. To investigate whether the basic principle underlying the aggregation process is common in prokaryotes and eukaryotes, we conducted a large-scale aggregation analysis of ~500 cytosolic budding yea...

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Detalles Bibliográficos
Autores principales: Uemura, Eri, Niwa, Tatsuya, Minami, Shintaro, Takemoto, Kazuhiro, Fukuchi, Satoshi, Machida, Kodai, Imataka, Hiroaki, Ueda, Takuya, Ota, Motonori, Taguchi, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766493/
https://www.ncbi.nlm.nih.gov/pubmed/29330519
http://dx.doi.org/10.1038/s41598-017-18977-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766493/
https://www.ncbi.nlm.nih.gov/pubmed/29330519
http://dx.doi.org/10.1038/s41598-017-18977-5

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