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Human Placental-Derived Adherent Stromal Cells Co-Induced with TNF-α and IFN-γ Inhibit Triple-Negative Breast Cancer in Nude Mouse Xenograft Models

Culturing 3D-expanded human placental-derived adherent stromal cells (ASCs) in the presence of tumor necrosis factor-alpha (TNF-α) and interferon-gamma (IFN-γ) transiently upregulated the secretion of numerous anti-proliferative, anti-angiogenic and pro-inflammatory cytokines. In a 3D-spheroid scree...

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Detalles Bibliográficos
Autores principales: Allen, Hoshea, Shraga-Heled, Niva, Blumenfeld, Michal, Dego-Ashto, Tamar, Fuchs-Telem, Dana, Gilert, Ariel, Aberman, Zami, Ofir, Racheli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766494/
https://www.ncbi.nlm.nih.gov/pubmed/29330447
http://dx.doi.org/10.1038/s41598-017-18428-1