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Human Placental-Derived Adherent Stromal Cells Co-Induced with TNF-α and IFN-γ Inhibit Triple-Negative Breast Cancer in Nude Mouse Xenograft Models
Culturing 3D-expanded human placental-derived adherent stromal cells (ASCs) in the presence of tumor necrosis factor-alpha (TNF-α) and interferon-gamma (IFN-γ) transiently upregulated the secretion of numerous anti-proliferative, anti-angiogenic and pro-inflammatory cytokines. In a 3D-spheroid scree...
Autores principales: | Allen, Hoshea, Shraga-Heled, Niva, Blumenfeld, Michal, Dego-Ashto, Tamar, Fuchs-Telem, Dana, Gilert, Ariel, Aberman, Zami, Ofir, Racheli |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766494/ https://www.ncbi.nlm.nih.gov/pubmed/29330447 http://dx.doi.org/10.1038/s41598-017-18428-1 |
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