Beta-catenin cleavage enhances transcriptional activation

Nuclear activation of Wnt/β-catenin signaling is required for cell proliferation in inflammation and cancer. Studies from our group indicate that β-catenin activation in colitis and colorectal cancer (CRC) correlates with increased nuclear levels of β-catenin phosphorylated at serine 552 (pβ-Cat(552...

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Detalles Bibliográficos
Autores principales: Goretsky, Tatiana, Bradford, Emily M., Ye, Qing, Lamping, Olivia F., Vanagunas, Tomas, Moyer, Mary Pat, Keller, Patrick C., Sinh, Preetika, Llovet, Josep M., Gao, Tianyan, She, Qing-Bai, Li, Linheng, Barrett, Terrence A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766502/
https://www.ncbi.nlm.nih.gov/pubmed/29330435
http://dx.doi.org/10.1038/s41598-017-18421-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766502/
https://www.ncbi.nlm.nih.gov/pubmed/29330435
http://dx.doi.org/10.1038/s41598-017-18421-8

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