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Dynamic modelling of the mTOR signalling network reveals complex emergent behaviours conferred by DEPTOR
The mechanistic Target of Rapamycin (mTOR) signalling network is an evolutionarily conserved network that controls key cellular processes, including cell growth and metabolism. Consisting of the major kinase complexes mTOR Complex 1 and 2 (mTORC1/2), the mTOR network harbours complex interactions an...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766521/ https://www.ncbi.nlm.nih.gov/pubmed/29330362 http://dx.doi.org/10.1038/s41598-017-18400-z |