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Induction of ferroptosis and mitochondrial dysfunction by oxidative stress in PC12 cells

Neurodegenerative diseases (NDD) are typically associated with neuron loss in nervous system areas. Interventions with related death mechanisms may ameliorate NDD progression. Oxidative stress plays an important role in NDD cell death routines. However, tert-butylhydroperoxide (t-BHP), a widely used...

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Detalles Bibliográficos
Autores principales: Wu, Chuanhong, Zhao, Wenwen, Yu, Jie, Li, Shaojing, Lin, Ligen, Chen, Xiuping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766540/
https://www.ncbi.nlm.nih.gov/pubmed/29330409
http://dx.doi.org/10.1038/s41598-017-18935-1