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Inactivated rotavirus vaccine by parenteral administration induces mucosal immunity in mice

To improve the safety and efficacy of oral rotavirus vaccines, we developed an inactivated rotavirus vaccine (IRV) for parenteral administration. Since it remains unknown whether parenteral vaccination can induce mucosal immunity, we performed a comprehensive assessment of immune responses to IRV in...

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Detalles Bibliográficos
Autores principales: Resch, Theresa K., Wang, Yuhuan, Moon, Sung-Sil, Joyce, Jessica, Li, Song, Prausnitz, Mark, Jiang, Baoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766576/
https://www.ncbi.nlm.nih.gov/pubmed/29330512
http://dx.doi.org/10.1038/s41598-017-18973-9