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Inactivated rotavirus vaccine by parenteral administration induces mucosal immunity in mice
To improve the safety and efficacy of oral rotavirus vaccines, we developed an inactivated rotavirus vaccine (IRV) for parenteral administration. Since it remains unknown whether parenteral vaccination can induce mucosal immunity, we performed a comprehensive assessment of immune responses to IRV in...
Autores principales: | Resch, Theresa K., Wang, Yuhuan, Moon, Sung-Sil, Joyce, Jessica, Li, Song, Prausnitz, Mark, Jiang, Baoming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766576/ https://www.ncbi.nlm.nih.gov/pubmed/29330512 http://dx.doi.org/10.1038/s41598-017-18973-9 |
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