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High STAP1 expression in DUX4-rearranged cases is not suitable as therapeutic target in pediatric B-cell precursor acute lymphoblastic leukemia

Approximately 25% of the pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL) cases are genetically unclassified. More thorough elucidation of the pathobiology of these genetically unclassified (‘B-other’) cases may identify novel treatment options. We analyzed gene expression profiles...

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Detalles Bibliográficos
Autores principales: Steeghs, Elisabeth M. P., Bakker, Marjolein, Hoogkamer, Alex Q., Boer, Judith M., Hartman, Quirine J., Stalpers, Femke, Escherich, Gabriele, de Haas, Valerie, de Groot-Kruseman, Hester A., Pieters, Rob, den Boer, Monique L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766593/
https://www.ncbi.nlm.nih.gov/pubmed/29330417
http://dx.doi.org/10.1038/s41598-017-17704-4