Cargando…
High STAP1 expression in DUX4-rearranged cases is not suitable as therapeutic target in pediatric B-cell precursor acute lymphoblastic leukemia
Approximately 25% of the pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL) cases are genetically unclassified. More thorough elucidation of the pathobiology of these genetically unclassified (‘B-other’) cases may identify novel treatment options. We analyzed gene expression profiles...
Autores principales: | Steeghs, Elisabeth M. P., Bakker, Marjolein, Hoogkamer, Alex Q., Boer, Judith M., Hartman, Quirine J., Stalpers, Femke, Escherich, Gabriele, de Haas, Valerie, de Groot-Kruseman, Hester A., Pieters, Rob, den Boer, Monique L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766593/ https://www.ncbi.nlm.nih.gov/pubmed/29330417 http://dx.doi.org/10.1038/s41598-017-17704-4 |
Ejemplares similares
-
Copy number alterations in B-cell development genes, drug resistance, and clinical outcome in pediatric B-cell precursor acute lymphoblastic leukemia
por: Steeghs, Elisabeth M. P., et al.
Publicado: (2019) -
JAK2 aberrations in childhood B-cell precursor acute lymphoblastic leukemia
por: Steeghs, Elisabeth M.P., et al.
Publicado: (2017) -
RAS pathway mutations as a predictive biomarker for treatment adaptation in pediatric B-cell precursor acute lymphoblastic leukemia
por: Jerchel, I S, et al.
Publicado: (2018) -
Tyrosine kinase fusion genes in pediatric BCR-ABL1-like acute lymphoblastic leukemia
por: Boer, Judith M., et al.
Publicado: (2016) -
DUX Hunting—Clinical Features and Diagnostic Challenges Associated with DUX4-Rearranged Leukaemia
por: Rehn, Jacqueline A., et al.
Publicado: (2020)