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Novel endogenous simian retroviral integrations in Vero cells: implications for quality control of a human vaccine cell substrate
African green monkey (AGM)-derived Vero cells have been utilized to produce various human vaccines. The Vero cell genome harbors a variety of simian endogenous type D retrovirus (SERV) sequences. In this study, a transcriptome analysis showed that DNA hypomethylation released the epigenetic repressi...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766633/ https://www.ncbi.nlm.nih.gov/pubmed/29330501 http://dx.doi.org/10.1038/s41598-017-18934-2 |