The Calcium-Induced Regulation in the Molecular and Transcriptional Circuitry of Human Inflammatory Response and Autoimmunity

Rheumatoid arthritis synovial fibroblasts (RASFs) are fundamental effector cells in RA driving the joint inflammation and deformities. Celastrol is a natural compound that exhibits a potent anti-arthritic effect promoting endoplasmic reticulum (ER) stress mediated by intracellular calcium (Ca(2+)) m...

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Detalles Bibliográficos
Autores principales: de Seabra Rodrigues Dias, Ivo R., Mok, Simon W. F., Gordillo-Martínez, Flora, Khan, Imran, Hsiao, Wendy W. L., Law, Betty Y. K., Wong, Vincent K. W., Liu, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766673/
https://www.ncbi.nlm.nih.gov/pubmed/29358919
http://dx.doi.org/10.3389/fphar.2017.00962

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766673/
https://www.ncbi.nlm.nih.gov/pubmed/29358919
http://dx.doi.org/10.3389/fphar.2017.00962

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