Pharmacogenomics of GPCR Drug Targets

Natural genetic variation in the human genome is a cause of individual differences in responses to medications and is an underappreciated burden on public health. Although 108 G-protein-coupled receptors (GPCRs) are the targets of 475 (∼34%) Food and Drug Administration (FDA)-approved drugs and acco...

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Detalles Bibliográficos
Autores principales: Hauser, Alexander S., Chavali, Sreenivas, Masuho, Ikuo, Jahn, Leonie J., Martemyanov, Kirill A., Gloriam, David E., Babu, M. Madan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766829/
https://www.ncbi.nlm.nih.gov/pubmed/29249361
http://dx.doi.org/10.1016/j.cell.2017.11.033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766829/
https://www.ncbi.nlm.nih.gov/pubmed/29249361
http://dx.doi.org/10.1016/j.cell.2017.11.033

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