Neurotransmitter Funneling Optimizes Glutamate Receptor Kinetics

Ionotropic glutamate receptors (iGluRs) mediate neurotransmission at the majority of excitatory synapses in the brain. Little is known, however, about how glutamate reaches the recessed binding pocket in iGluR ligand-binding domains (LBDs). Here we report the process of glutamate binding to a protot...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Alvin, Salazar, Héctor, Plested, Andrew J.R., Lau, Albert Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766834/
https://www.ncbi.nlm.nih.gov/pubmed/29249286
http://dx.doi.org/10.1016/j.neuron.2017.11.024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766834/
https://www.ncbi.nlm.nih.gov/pubmed/29249286
http://dx.doi.org/10.1016/j.neuron.2017.11.024

Ejemplares similares