Mechanism of polypurine tract primer generation by HIV-1 reverse transcriptase

HIV-1 reverse transcriptase (RT) possesses both DNA polymerase activity and RNase H activity that act in concert to convert single-stranded RNA of the viral genome to double-stranded DNA that is then integrated into the DNA of the infected cell. Reverse transcriptase–catalyzed reverse transcription...

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Detalles Bibliográficos
Autores principales: Figiel, Małgorzata, Krepl, Miroslav, Park, Sangwoo, Poznański, Jarosław, Skowronek, Krzysztof, Gołąb, Agnieszka, Ha, Taekjip, Šponer, Jiří, Nowotny, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2018
Materias:
Enzymology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766924/
https://www.ncbi.nlm.nih.gov/pubmed/29122886
http://dx.doi.org/10.1074/jbc.M117.798256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766924/
https://www.ncbi.nlm.nih.gov/pubmed/29122886
http://dx.doi.org/10.1074/jbc.M117.798256

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