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Isolation of anti-extra-cellular vesicle single-domain antibodies by direct panning on vesicle-enriched fractions
BACKGROUND: The thorough understanding of the physiological and pathological processes mediated by extracellular vesicles (EVs) is challenged by purification methods which are cumbersome, not reproducible, or insufficient to yield homogeneous material. Chromatography based on both ion-exchange and i...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766977/ https://www.ncbi.nlm.nih.gov/pubmed/29331148 http://dx.doi.org/10.1186/s12934-017-0856-9 |