Evidence for the activation of pyroptotic and apoptotic pathways in RPE cells associated with NLRP3 inflammasome in the rodent eye

BACKGROUND: Age-related macular degeneration (AMD) is a devastating eye disease causing irreversible vision loss in the elderly. Retinal pigment epithelium (RPE), the primary cell type that is afflicted in AMD, undergoes programmed cell death in the late stages of the disease. However, the exact mec...

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Detalles Bibliográficos
Autores principales: Gao, Jiangyuan, Cui, Jing Z., To, Eleanor, Cao, Sijia, Matsubara, Joanne A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766992/
https://www.ncbi.nlm.nih.gov/pubmed/29329580
http://dx.doi.org/10.1186/s12974-018-1062-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766992/
https://www.ncbi.nlm.nih.gov/pubmed/29329580
http://dx.doi.org/10.1186/s12974-018-1062-3

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