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Treating C3 glomerulopathy with eculizumab

BACKGROUND: C3 glomerulopathy (C3G) is a rare, but severe glomerular disease with grim prognosis. The complex pathogenesis is just unfolding, and involves acquired as well as inherited dysregulation of the alternative pathway of the complement cascade. Currently, there is no established therapy. Tre...

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Detalles Bibliográficos
Autores principales: Welte, Thomas, Arnold, Frederic, Kappes, Julia, Seidl, Maximilian, Häffner, Karsten, Bergmann, Carsten, Walz, Gerd, Neumann-Haefelin, Elke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767001/
https://www.ncbi.nlm.nih.gov/pubmed/29329521
http://dx.doi.org/10.1186/s12882-017-0802-4