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Over-expression of ARHGAP18 suppressed cell proliferation, migration, invasion, and tumor growth in gastric cancer by restraining over-activation of MAPK signaling pathways

Globally, gastric cancer is the second-greatest cause of cancer death. ARHGAP18 belongs to the Rho family of GTPases which is involved in cellular migration, invasion, and growth phases. The aim of the present study was to investigate whether ARHGAP18 could regulate cell proliferation, migration, in...

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Detalles Bibliográficos
Autores principales: Li, Yan, Ji, Shan, Fu, Liye, Jiang, Tao, Wu, Di, Meng, Fandong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767098/
https://www.ncbi.nlm.nih.gov/pubmed/29386906
http://dx.doi.org/10.2147/OTT.S130255