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Novel Cysteine Desulfidase CdsB Involved in Releasing Cysteine Repression of Toxin Synthesis in Clostridium difficile

Clostridium difficile, a major cause of nosocomial diarrhea and pseudomembranous colitis, still poses serious health-care challenges. The expression of its two main virulence factors, TcdA and TcdB, is reportedly repressed by cysteine, but molecular mechanism remains unclear. The cysteine desulfidas...

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Detalles Bibliográficos
Autores principales: Gu, Huawei, Yang, Yingyin, Wang, Meng, Chen, Shuyi, Wang, Haiying, Li, Shan, Ma, Yi, Wang, Jufang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767170/
https://www.ncbi.nlm.nih.gov/pubmed/29376034
http://dx.doi.org/10.3389/fcimb.2017.00531