Expression of matrix metalloproteinase 12 is highly specific for non-proliferating invasive trophoblasts in the first trimester and temporally regulated by oxygen-dependent mechanisms including HIF-1A

During first trimester pregnancy, trophoblast cells invade from the placenta into the maternal decidua where they anchor the placenta and remodel luminal structures like spiral arteries. This process depends on proteases secreted by invading trophoblasts, which degrade extracellular matrix (ECM). We...

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Detalles Bibliográficos
Autores principales: Hiden, Ursula, Eyth, Christian P., Majali-Martinez, Alejandro, Desoye, Gernot, Tam-Amersdorfer, Carmen, Huppertz, Berthold, Ghaffari Tabrizi-Wizsy, Nassim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767211/
https://www.ncbi.nlm.nih.gov/pubmed/28990117
http://dx.doi.org/10.1007/s00418-017-1608-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767211/
https://www.ncbi.nlm.nih.gov/pubmed/28990117
http://dx.doi.org/10.1007/s00418-017-1608-y

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