The Calcineurin Inhibitor FK506 Prevents Cognitive Impairment by Inhibiting Reactive Astrogliosis in Pilocarpine-Induced Status Epilepticus Rats

Status epilepticus (SE) is a severe clinical manifestation of epilepsy accompanying with cognitive impairment and brain damage. Astrocyte activation occurs following seizures and plays an important role in epilepsy-induced pathological injury, including cognitive impairment. FK506, an immunosuppress...

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Detalles Bibliográficos
Autores principales: Liu, Jinzhi, Si, Zhihua, Li, Shuqing, Huang, Zhan, He, Yan, Zhang, Tao, Wang, Aihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767224/
https://www.ncbi.nlm.nih.gov/pubmed/29375315
http://dx.doi.org/10.3389/fncel.2017.00428

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767224/
https://www.ncbi.nlm.nih.gov/pubmed/29375315
http://dx.doi.org/10.3389/fncel.2017.00428

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