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Icariin Reduces Dopaminergic Neuronal Loss and Microglia-Mediated Inflammation in Vivo and in Vitro

Parkinson’s disease (PD) is one of the most common neurodegenerative diseases characterized with a gradual loss of midbrain substantia nigra (SN) dopamine (DA) neurons. An excessive evidence demonstrated that microglia-mediated inflammation might be involved in the pathogenesis of PD. Thus, inhibiti...

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Detalles Bibliográficos
Autores principales: Wang, Guo-Qing, Li, Dai-Di, Huang, Chun, Lu, Di-Sheng, Zhang, Chao, Zhou, Shao-Yu, Liu, Jie, Zhang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767257/
https://www.ncbi.nlm.nih.gov/pubmed/29375304
http://dx.doi.org/10.3389/fnmol.2017.00441