Traditional Herbal Medicine-Derived Sulforaphene LFS-01 Reverses Colitis in Mice by Selectively Altering the Gut Microbiota and Promoting Intestinal Gamma-Delta T Cells

Sulforaphene (LFS-01) is a natural compound derived from traditional herbal medicine. Here, we show that oral administration of LFS-01 is able to dramatically alter the skewed gut microbiota and reverse colitis in model mice associated with an increase of intestinal γδT cells. Through 16S rDNA seque...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Ming, Gao, Jiali, Tang, Yan, Liu, Meishuo, Wu, Sijin, Qu, Kunli, Long, Xiangyu, Li, Huajun, Liu, Min, Liu, Yinhui, Yuan, Jieli, Mao, Lei, Liu, Yu, Zheng, Xiliang, Wang, Erkang, Wang, Jin, Yang, Yongliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767259/
https://www.ncbi.nlm.nih.gov/pubmed/29375374
http://dx.doi.org/10.3389/fphar.2017.00959

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767259/
https://www.ncbi.nlm.nih.gov/pubmed/29375374
http://dx.doi.org/10.3389/fphar.2017.00959

Ejemplares similares