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Intense Activity of the Raphe Spinal Pathway Depresses Motor Activity via a Serotonin Dependent Mechanism

Motor fatigue occurring during prolonged physical activity has both peripheral and central origins. It was previously demonstrated that the excitability of motoneurons was decreased when a spillover of serotonin could activate extrasynaptic 5-HT(1A) receptors at the axon initial segment (AIS) of mot...

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Detalles Bibliográficos
Autores principales: Perrier, Jean-François, Rasmussen, Hanne B., Jørgensen, Lone K., Berg, Rune W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767281/
https://www.ncbi.nlm.nih.gov/pubmed/29375322
http://dx.doi.org/10.3389/fncir.2017.00111