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Drug–Target Kinetics in Drug Discovery
[Image: see text] The development of therapies for the treatment of neurological cancer faces a number of major challenges including the synthesis of small molecule agents that can penetrate the blood-brain barrier (BBB). Given the likelihood that in many cases drug exposure will be lower in the CNS...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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American Chemical Society
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767540/ https://www.ncbi.nlm.nih.gov/pubmed/28640596 http://dx.doi.org/10.1021/acschemneuro.7b00185 |