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Drug–Target Kinetics in Drug Discovery

[Image: see text] The development of therapies for the treatment of neurological cancer faces a number of major challenges including the synthesis of small molecule agents that can penetrate the blood-brain barrier (BBB). Given the likelihood that in many cases drug exposure will be lower in the CNS...

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Detalles Bibliográficos
Autor principal: Tonge, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767540/
https://www.ncbi.nlm.nih.gov/pubmed/28640596
http://dx.doi.org/10.1021/acschemneuro.7b00185