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Blocking LPA-dependent signaling increases ovarian cancer cell death in response to chemotherapy
The paradoxical role of reactive oxygen species in cell death versus cell survival establishes a delicate balance between chemotherapy efficacy and management of detrimental side effects. Normal proliferative signaling requires that cells remain inside a redox range that allows reversible protein ox...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767563/ https://www.ncbi.nlm.nih.gov/pubmed/29331665 http://dx.doi.org/10.1016/j.redox.2018.01.002 |