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Blocking LPA-dependent signaling increases ovarian cancer cell death in response to chemotherapy

The paradoxical role of reactive oxygen species in cell death versus cell survival establishes a delicate balance between chemotherapy efficacy and management of detrimental side effects. Normal proliferative signaling requires that cells remain inside a redox range that allows reversible protein ox...

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Detalles Bibliográficos
Autores principales: Rogers, LeAnn C., Davis, Ryan R., Said, Naveen, Hollis, Thomas, Daniel, Larry W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767563/
https://www.ncbi.nlm.nih.gov/pubmed/29331665
http://dx.doi.org/10.1016/j.redox.2018.01.002