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Blocking LPA-dependent signaling increases ovarian cancer cell death in response to chemotherapy

The paradoxical role of reactive oxygen species in cell death versus cell survival establishes a delicate balance between chemotherapy efficacy and management of detrimental side effects. Normal proliferative signaling requires that cells remain inside a redox range that allows reversible protein ox...

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Detalles Bibliográficos
Autores principales:	Rogers, LeAnn C., Davis, Ryan R., Said, Naveen, Hollis, Thomas, Daniel, Larry W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767563/ https://www.ncbi.nlm.nih.gov/pubmed/29331665 http://dx.doi.org/10.1016/j.redox.2018.01.002

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