Alphavirus Replicon DNA Vectors Expressing Ebola GP and VP40 Antigens Induce Humoral and Cellular Immune Responses in Mice

Ebola virus (EBOV) causes severe hemorrhagic fevers in humans, and no approved therapeutics or vaccine is currently available. Glycoprotein (GP) is the major protective antigen of EBOV, and can generate virus-like particles (VLPs) by co-expression with matrix protein (VP40). In this study, we constr...

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Detalles Bibliográficos
Autores principales: Ren, Shoufeng, Wei, Qimei, Cai, Liya, Yang, Xuejing, Xing, Cuicui, Tan, Feng, Leavenworth, Jianmei W., Liang, Shaohui, Liu, Wenquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767729/
https://www.ncbi.nlm.nih.gov/pubmed/29375526
http://dx.doi.org/10.3389/fmicb.2017.02662

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767729/
https://www.ncbi.nlm.nih.gov/pubmed/29375526
http://dx.doi.org/10.3389/fmicb.2017.02662

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