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Covalent Lectin Inhibition and Application in Bacterial Biofilm Imaging

Biofilm formation by pathogenic bacteria is a hallmark of chronic infections. In many cases, lectins play key roles in establishing biofilms. The pathogen Pseudomonas aeruginosa often exhibiting various drug resistances employs its lectins LecA and LecB as virulence factors and biofilm building bloc...

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Detalles Bibliográficos
Autores principales: Wagner, Stefanie, Hauck, Dirk, Hoffmann, Michael, Sommer, Roman, Joachim, Ines, Müller, Rolf, Imberty, Anne, Varrot, Annabelle, Titz, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767747/
https://www.ncbi.nlm.nih.gov/pubmed/28960731
http://dx.doi.org/10.1002/anie.201709368