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Mitochondrial intermediate peptidase is a novel regulator of sirtuin‐3 activation by caloric restriction
Sirtuin‐3 (SIRT3) regulates mitochondrial quality and is involved in the anti‐ageing and pro‐longevity actions of caloric restriction (CR). Here, we show that CR upregulates the mature form of SIRT3 and mitochondrial intermediate peptidase (MIPEP), a mitochondrial signal peptidase (MtSPase), in whit...
Autores principales: | Kobayashi, Masaki, Takeda, Kanae, Narita, Takumi, Nagai, Keita, Okita, Naoyuki, Sudo, Yuka, Miura, Yuri, Tsumoto, Hiroki, Nakagawa, Yoshimi, Shimano, Hitoshi, Higami, Yoshikazu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767765/ https://www.ncbi.nlm.nih.gov/pubmed/29151261 http://dx.doi.org/10.1002/1873-3468.12914 |
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