Mitochondrial intermediate peptidase is a novel regulator of sirtuin‐3 activation by caloric restriction

Sirtuin‐3 (SIRT3) regulates mitochondrial quality and is involved in the anti‐ageing and pro‐longevity actions of caloric restriction (CR). Here, we show that CR upregulates the mature form of SIRT3 and mitochondrial intermediate peptidase (MIPEP), a mitochondrial signal peptidase (MtSPase), in whit...

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Detalles Bibliográficos
Autores principales: Kobayashi, Masaki, Takeda, Kanae, Narita, Takumi, Nagai, Keita, Okita, Naoyuki, Sudo, Yuka, Miura, Yuri, Tsumoto, Hiroki, Nakagawa, Yoshimi, Shimano, Hitoshi, Higami, Yoshikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Letters
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767765/
https://www.ncbi.nlm.nih.gov/pubmed/29151261
http://dx.doi.org/10.1002/1873-3468.12914

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767765/
https://www.ncbi.nlm.nih.gov/pubmed/29151261
http://dx.doi.org/10.1002/1873-3468.12914

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