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Cathepsin B overexpression induces degradation of perilipin 1 to cause lipid metabolism dysfunction in adipocytes

Obesity, caused by the dysfunction of white adipose tissue (WAT), is reportedly accompanied by exacerbation of lipolysis. Perilipin 1 (PLIN1), which forms a coat around lipid droplets, interacts with several lipolysis proteins to regulate lipolysis. While it is known that perilipin family proteins a...

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Detalles Bibliográficos
Autores principales: Mizunoe, Yuhei, Kobayashi, Masaki, Hoshino, Shunsuke, Tagawa, Ryoma, Itagawa, Rei, Hoshino, Ayana, Okita, Naoyuki, Sudo, Yuka, Nakagawa, Yoshimi, Shimano, Hitoshi, Higami, Yoshikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971249/
https://www.ncbi.nlm.nih.gov/pubmed/31959889
http://dx.doi.org/10.1038/s41598-020-57428-6