Failed mitochondrial import and impaired proteostasis trigger SUMOylation of mitochondrial proteins

Modification by the ubiquitin-like protein SUMO affects hundreds of cellular substrate proteins and regulates a wide variety of physiological processes. While the SUMO system appears to predominantly target nuclear proteins and, to a lesser extent, cytosolic proteins, hardly anything is known about...

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Detalles Bibliográficos
Autores principales: Paasch, Florian, den Brave, Fabian, Psakhye, Ivan, Pfander, Boris, Jentsch, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2018
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767865/
https://www.ncbi.nlm.nih.gov/pubmed/29183993
http://dx.doi.org/10.1074/jbc.M117.817833

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767865/
https://www.ncbi.nlm.nih.gov/pubmed/29183993
http://dx.doi.org/10.1074/jbc.M117.817833

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