Extracellular acidification induces ROS- and mPTP-mediated death in HEK293 cells

The extracellular pH (pHe) is a key determinant of the cellular (micro)environment and needs to be maintained within strict boundaries to allow normal cell function. Here we used HEK293 cells to study the effects of pHe acidification (24 h), induced by mitochondrial inhibitors (rotenone, antimycin A...

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Detalles Bibliográficos
Autores principales: Teixeira, José, Basit, Farhan, Swarts, Herman G., Forkink, Marleen, Oliveira, Paulo J., Willems, Peter H.G.M., Koopman, Werner J.H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767902/
https://www.ncbi.nlm.nih.gov/pubmed/29331741
http://dx.doi.org/10.1016/j.redox.2017.12.018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767902/
https://www.ncbi.nlm.nih.gov/pubmed/29331741
http://dx.doi.org/10.1016/j.redox.2017.12.018

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