Mitochondrial pathway-mediated apoptosis is associated with erlotinib-induced cytotoxicity in hepatic cells

For advanced non-small-cell lung cancer (NSCLC) with mutations to the epidermal growth factor receptor (EGFR), EGFR tyrosine kinase inhibitors, including erlotinib are indicated for the first-line treatment. Liver injury is one of the multiple adverse effects of erlotinib and may affect its safety....

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Detalles Bibliográficos
Autores principales: Chen, Xueqin, Yang, Shaoyu, Pan, Yuelong, Li, Xin, Ma, Shenglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768067/
https://www.ncbi.nlm.nih.gov/pubmed/29387241
http://dx.doi.org/10.3892/ol.2017.7359

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768067/
https://www.ncbi.nlm.nih.gov/pubmed/29387241
http://dx.doi.org/10.3892/ol.2017.7359

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