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LIM kinase 1 serves an important role in the multidrug resistance of osteosarcoma cells

Multidrug resistance (MDR) is a major challenge for the management of the majority of cancers. The precise molecular mechanisms of MDR remain elusive. In a previous study, a multidrug resistant osteosarcoma model [MG63/vincristine (VCR)] was established by intermittent exposure of MG63 cells to grad...

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Detalles Bibliográficos
Autores principales: Yang, Jian-Zeng, Huang, Li-Hong, Chen, Rui, Meng, Ling-Jie, Gao, Yi-Yao, Ji, Qiu-Ye, Wang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768095/
https://www.ncbi.nlm.nih.gov/pubmed/29387219
http://dx.doi.org/10.3892/ol.2017.7317