Pichia pastoris-Expressed Bivalent Virus-Like Particulate Vaccine Induces Domain III-Focused Bivalent Neutralizing Antibodies without Antibody-Dependent Enhancement in Vivo

Dengue, a significant public health problem in several countries around the world, is caused by four different serotypes of mosquito-borne dengue viruses (DENV-1, -2, -3, and -4). Antibodies to any one DENV serotype which can protect against homotypic re-infection, do not offer heterotypic cross-pro...

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Detalles Bibliográficos
Autores principales: Shukla, Rahul, Rajpoot, Ravi K., Arora, Upasana, Poddar, Ankur, Swaminathan, Sathyamangalam, Khanna, Navin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768101/
https://www.ncbi.nlm.nih.gov/pubmed/29367852
http://dx.doi.org/10.3389/fmicb.2017.02644

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768101/
https://www.ncbi.nlm.nih.gov/pubmed/29367852
http://dx.doi.org/10.3389/fmicb.2017.02644

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