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Celastrus orbiculatus extracts induce apoptosis and inhibit invasion by targeting the maspin gene in human gastric adenocarcinoma cells

Celastrus orbiculatus Thunb. has been used as a remedy against cancer and inflammatory diseases for thousands of years in China. Maspin is expressed in normal cells and downregulated in prostate tumor cells. The underlying mechanisms between C. orbiculatus extract (COE) and maspin remain unclear. In...

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Detalles Bibliográficos
Autores principales: Qian, Yayun, Lu, Songhua, Shi, Youyang, Zhao, Xueyu, Yang, Ting, Jin, Feng, Liu, Yanqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768137/
https://www.ncbi.nlm.nih.gov/pubmed/29387218
http://dx.doi.org/10.3892/ol.2017.7341