B Cell-Intrinsic Role for IRF5 in TLR9/BCR-Induced Human B Cell Activation, Proliferation, and Plasmablast Differentiation

Upon recognition of antigen, B cells undergo rapid proliferation followed by differentiation to specialized antibody secreting cells (ASCs). During this transition, B cells are reliant upon a multilayer transcription factor network to achieve a dramatic remodeling of the B cell transcriptional lands...

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Detalles Bibliográficos
Autores principales: De, Saurav, Zhang, Baohong, Shih, Tiffany, Singh, Sukhwinder, Winkler, Aaron, Donnelly, Robert, Barnes, Betsy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768180/
https://www.ncbi.nlm.nih.gov/pubmed/29367853
http://dx.doi.org/10.3389/fimmu.2017.01938

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768180/
https://www.ncbi.nlm.nih.gov/pubmed/29367853
http://dx.doi.org/10.3389/fimmu.2017.01938

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